Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 4-[(2,4-Dichlorobenzoyl)amino]-2-chlorobenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 2,4-Dichlorobenzyl chloride | HCID 7212 | — |
| 반응물 | 4-Amino-2-chlorobenzoic acid | HCID 17154 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 4-[(2,4-Dichlorobenzoyl)amino]-2-chlorobenzoic acid | HCID 21836975 | — |
반응 단계
To a stirred mixture of 5.19 g of 2-chloro-4-aminobenzoic acid in 150 ml of methylene chloride is added 7.86 g of N,N-diisopropylethylamine and 12.67 g of 2,4-dichlorobenzylchloride and stirring continued for 18 hours. Water is added to the filtrate and the organic layer dried with Na2SO4 and concentrated in vacuo to give 13.68 g of the desired product, m.p. 171°-175° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05624923 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-2c6344183756424e98f2f44acba664c9 |
| 출처 메모 | uspto-grants-1997_04 |