2-Amino-6-methylpyridine → 2'-Chloro-6-methyl-[4,4']bipyridinyl-2-carboxylic acid (6-methyl-pyridin-2-yl)-amide
반응식
C(O[C:4]([C:6]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][N:15]=[C:14]([Cl:18])[CH:13]=2)[CH:9]=[C:8]([CH3:19])[N:7]=1)=[O:5])C.[NH2:20][C:21]1[CH:26]=[CH:25][CH:24]=[C:23]([CH3:27])[N:22]=1>>[CH3:27][C:23]1[N:22]=[C:21]([NH:20][C:4]([C:6]2[CH:11]=[C:10]([C:12]3[CH:17]=[CH:16][N:15]=[C:14]([Cl:18])[CH:13]=3)[CH:9]=[C:8]([CH3:19])[N:7]=2)=[O:5])[CH:26]=[CH:25][CH:24]=1참가 물질
3
실험 절차
The title compound, was prepared from 2′-Chloro-6-methyl-[4,4′]bipyridinyl-2-carboxylic acid ethyl ester in accordance with the general method of example 26, step 6 using 2-amino-6methylpyridine instead of 3-chloroaniline to yield the final compound as a white crystalline, MS (ISP): m/e=339.2, 341.1 (M+H)+.
출처 및 근거
- ORD 기록
- ord-47cdd614c33347c8a6a86985ded37fb5
- 출처 데이터셋
- uspto-grants-2011_05
- 특허 번호
- US07951824B2
반응 노트
불러오는 중…