Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromodecane → 3-{6-[2-(4-Methoxycarbonylphenyl)-ethinyl]-3-decyloxy-2-pyridyl}-propionic acid methyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromodecane | HCID 8173 | — |
| 반응물 | 3-{3-Hydroxy-6-[2-(4-methoxycarbonylphenyl)-ethinyl]-2-pyridyl}-propionic acid methyl ester | HCID 54181731 | — |
| 생성물 | 3-{6-[2-(4-Methoxycarbonylphenyl)-ethinyl]-3-decyloxy-2-pyridyl}-propionic acid methyl ester | HCID 53849573 | 75.1% |
반응 단계
Under the conditions of example 1 D, 500 mg of 3-{3-hydroxy-6-[2-(4-methoxycarbonylphenyl)-ethinyl]-2-pyridyl}-propionic acid methyl ester is reacted with 358 mg of 1-decyl bromide and worked up. 531 mg of 3-{6-[2-(4-methoxycarbonylphenyl)-ethinyl]-3-decyloxy-2-pyridyl}-propionic acid methyl ester of melting point 88°-90° C. is obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05624943 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-b774aba3e6684786b9cf5a41b3bd4b83 |
| 출처 메모 | uspto-grants-1997_04 |