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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 553147생성일: 2026년 10월 26일

6-Chloro-2-tetralone → 2-(6-Chloro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide

https://huagongshe.com/reaction/553147

반응식

참여 물질

역할이름HCID투입량
반응물6-Chloro-2-tetraloneHCID 4456139—
반응물2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amideHCID 67164226—
생성물2-(6-Chloro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amideHCID 11641379—

반응 단계

2-Amino-pentanoic acid [1-(1,1-dimethyl-2-pyrrolidin-1-yl-ethyl)-1H-imidazol-4-yl]-amide was reacted with 6-chloro-3,4-dihydro-1H-naphthalen-2-one to provide the title compound: C13 NMR (100 MHz, CDCl3) 14.2, 19.6, 19.6, 24.3, 26.6, 27.9, 28.0, 29.2, 30.0, 36.0, 36.5, 36.6, 36.9, 53.1, 53.3, 56.0, 59.1, 60.5, 60.8, 67.3, 104.7, 126.1, 128.5, 128.7, 130.7, 130.8, 131.2, 131.5, 131.6, 133.6, 137.3, 137.7, 138.0, 172.4; MS m/z 472.4 (M+1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07951958B2
출처 데이터셋uspto-grants-2011_05
ORD IDord-1d68aa5c3dde41e1996a4e317cfbb73c
출처 메모uspto-grants-2011_05