Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl chloroacetate → Ethyl sulfoacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl chloroacetate | HCID 7751 | — |
| 반응물 | Sodium Sulfite | HCID 24437 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Ethyl sulfoacetate | HCID 12216623 | 100.1% |
반응 단계
To a solution of Na2SO3 (10 g, 79 mmol.) in 50 mL of H2O was added a solution of ethyl 2-chloroacetate (12.7 mL, 119 mmol.) in 55 mL of EtOH. The mixture was heated at reflux for 6 h, after which time all the volatiles were removed by evaporation under reduced pressure. The concentrated materials were dried to afford crude (ethoxycarbonyl)methanesulfonic acid (13.3 g, 100%) used directly without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08048862B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-c88b6db0b6db47158d18750b41bcb397 |
| 출처 메모 | uspto-grants-2011_11 |