Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Bromophenylacetic acid → (4'-{4-[1-(2-Chloro-phenyl)-ethoxycarbonylamino]-3-methyl-isoxazol-5-yl}-biphenyl-2-yl)-acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Bromophenylacetic acid | HCID 87754 | — |
| 반응물 | {3-Methyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-isoxazol-4-yl}-carbamic acid 1-(2-chloro-phenyl)-ethyl ester | HCID 67350448 | — |
| 생성물 | (4'-{4-[1-(2-Chloro-phenyl)-ethoxycarbonylamino]-3-methyl-isoxazol-5-yl}-biphenyl-2-yl)-acetic acid | HCID 46239907 | — |
반응 단계
Prepared according to the procedure described in Example 19, Step 1 using {3-methyl-5-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-isoxazol-4-yl}-carbamic acid 1-(2-chloro-phenyl)-ethyl ester and 2-bromophenylacetic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08048902B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-8d32c2cd3b484265b1c4a5c542a7d255 |
| 출처 메모 | uspto-grants-2011_11 |