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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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(6R*,9aS*)-6-(4-methoxyphenyl)-3,6,7,8,9,9a-hexahydroquinolizin-4-one → (6R*,9aS*)-6-(4-methoxyphenyl)octahydroquinolizin-4-one

HRID 553879
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인쇄 미리보기

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HRID 553879 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C@H:9]2[CH2:18][CH2:17][CH2:16][C@@H:15]3[N:10]2[C:11](=[O:19])[CH2:12][CH:13]=[CH:14]3)=[CH:5][CH:4]=1.[H][H]>CO.[Pt]=O>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C@H:9]2[CH2:18][CH2:17][CH2:16][C@@H:15]3[N:10]2[C:11](=[O:19])[CH2:12][CH2:13][CH2:14]3)=[CH:7][CH:8]=1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 2

HCID 69072392(6R*,9aS*)-6-(4-methoxyphenyl)-3,6,7,8,9,9a-hexahydroquinolizin-4-oneHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 69070867(6R*,9aS*)-6-(4-methoxyphenyl)octahydroquinolizin-4-one수율 81.5%

시약·촉매·용매 2

HCID 82844Platinum oxide (PtO)촉매HCID 887Methanol용매

실험 절차

Platinum oxide (2 mg) was added to a solution of (6R*,9aS*)-6-(4-methoxyphenyl)-3,6,7,8,9,9a-hexahydroquinolizin-4-one (28 mg) in methanol (5 mL), and the reaction solution was stirred in a hydrogen stream at room temperature for 13 hours. The reaction solution was filtered through celite, and the filtrate was concentrated under reduced pressure to obtain 23 mg of the title compound. The property values of the compound are as follows.

후처리

  1. filtrationThe reaction solution was filtered through celite
  2. concentrationthe filtrate was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-962f1dadef664bf0a55ec32702bb57ad
출처 데이터셋
uspto-grants-2011_11
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US08048878B2

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