Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tosylmethyl isocyanide → Ethyl 4-methyl-1h-pyrrole-3-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tosylmethyl isocyanide | HCID 161915 | — |
| 반응물 | Ethyl trans-crotonate | HCID 429065 | — |
| 반응물 | Potassium tert-butoxide | HCID 23665647 | — |
| 생성물 | Ethyl 4-methyl-1h-pyrrole-3-carboxylate | HCID 235044 | 71.1% |
반응 단계
Using p-toluenesulfonylmethyl isocyanide (8.55 g), ethyl crotonate (5.0 g) and potassium tert-butoxide (5.90 g), a procedure as in Reference Example 39 was performed to give the title compound as a pale-yellow solid (yield 4.77 g, 71%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08048909B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-c31a5c841b6e47ee8805ad48720a6c35 |
| 출처 메모 | uspto-grants-2011_11 |