Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium borohydride → methyl 3-({4-[(methylamino)methyl]-2-phenyl-1H-pyrrol-1-yl}sulfonyl)benzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | Monomethylamine methanol | HCID 57454252 | — |
| 반응물 | Methyl 3-[(4-formyl-2-phenyl-1H-pyrrol-1-yl)sulfonyl]benzoate | HCID 86620754 | — |
| 생성물 | methyl 3-({4-[(methylamino)methyl]-2-phenyl-1H-pyrrol-1-yl}sulfonyl)benzoate | HCID 66924818 | 49% |
반응 단계
Using methyl 3-[(4-formyl-2-phenyl-1H-pyrrol-1-yl)sulfonyl]benzoate (1.32 g), 40% methylamine methanol solution (416 mg) and sodium borohydride (100 mg), a procedure as in Reference Example 145 was performed to give the title compound as a pale-yellow oil (yield 668 mg, 49%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08048909B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-3a72096dbdbd4086af1d88cd25cb363e |
| 출처 메모 | uspto-grants-2011_11 |