Nitric Acid → 4'-Bromo-3'-nitropropiophenone

HRID 554765

반응식

HRID 554765 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:11])[CH2:9][CH3:10])=[CH:4][CH:3]=1.[N+:12]([O-])([OH:14])=[O:13]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:8](=[O:11])[CH2:9][CH3:10])=[CH:6][C:7]=1[N+:12]([O-:14])=[O:13]

참가 물질

3

반응물 2

HCID 944Nitric AcidHCID 66312p-Bromopropiophenone

생성물 1

HCID 33626924'-Bromo-3'-nitropropiophenone

실험 절차

To fuming nitric acid (200 ml), 1-(4-bromophenyl)-1-propanone (40 g) was added while keeping the inside temperature of the mixture at 5 to 10° C. The reaction solution was stirred at that temperature for 30 minutes and then poured into ice. The precipitate was collected by filtration, washed with distilled water, and recrystallized from methanol to obtain the title compound (18 g).

후처리

  1. customat 5 to 10° C
  2. additionpoured into ice
  3. filtrationThe precipitate was collected by filtration
  4. washwashed with distilled water
  5. customrecrystallized from methanol

출처 및 근거

ORD 기록
ord-a81ca471e88e4dbcaec8de4654b22bb2
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08049006B2

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