Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aniline → N-[(1R)-2-anilino-1-methyl-2-oxoethyl]-6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aniline | HCID 6115 | — |
| 반응물 | Glycine tert-butyl ester hydrochloride | HCID 2725036 | — |
| 반응물 | Tert-butyl {[2-({[6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-yl]carbonyl}amino)butanoyl]amino}acetate | HCID 76588771 | — |
| 생성물 | N-[(1R)-2-anilino-1-methyl-2-oxoethyl]-6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-carboxamide | HCID 57671048 | — |
반응 단계
Instead of the starting material of Example 220, that is, the compound 119, the compound 100 was used, while instead of the glycine tert-butyl ester hydrochloride, aniline was used for the similar procedure as in Example 220 to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08049006B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-0c1535f2cebe490ea1ca2562f7d468a6 |
| 출처 메모 | uspto-grants-2011_11 |