Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Glycine tert-butyl ester hydrochloride → N-{(1R)-1-[(tert-butoxyamino)carbonyl]propyl}-6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-carboxamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Glycine tert-butyl ester hydrochloride | HCID 2725036 | — |
| 반응물 | Tert-butyl {[2-({[6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-yl]carbonyl}amino)butanoyl]amino}acetate | HCID 76588771 | — |
| 생성물 | N-{(1R)-1-[(tert-butoxyamino)carbonyl]propyl}-6-(5-chloro-2-methoxybenzyl)-3,7-dioxo-1,4-diazepan-1-carboxamide | HCID 57671032 | — |
반응 단계
Instead of the starting material compound of Example 220, that is, glycine tert-butyl ester hydrochloride, O-(tert-butyl)hydroxylaminehydrochloride was used for the similar procedure as in Example 220 to obtain the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08049006B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-c9be101665be45eca9421a4bc079276f |
| 출처 메모 | uspto-grants-2011_11 |