(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate → HCID 86661985, 화합물

반응식

[N:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[O:16]1[CH2:18][CH:17]1[CH2:19]OS(C1C=CC=C([N+]([O-])=O)C=1)(=O)=O>>[O:16]1[CH2:18][CH:17]1[CH2:19][N:13]1[CH2:12][CH2:11][N:10]([CH2:9][CH2:8][CH2:7][N:1]2[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]2)[CH2:15][CH2:14]1

참가 물질

반응물 2

HCID 286836(Oxiran-2-yl)methyl 3-nitrobenzene-1-sulfonate

HCID 27372531-(3-Piperidinopropyl)piperazine

생성물 1

HCID 86661985HCID 86661985, 화합물수율 64%

실험 절차

The same method as employed in the preparation of Intermediate 1 but starting from 1-(3-piperidin-1-ylpropyl)piperazine and (±)-3-nitro-benzenesulfonic acid oxiranylmethyl ester gives after flash chromatography the title compound as an orange oil in a 64% yield.

출처 및 근거

ORD 기록: ord-b454a9d2464541f38c798304fbc52685
출처 데이터셋: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08053436B1

반응 노트

불러오는 중…