4-Nitrophenol → Oxalic acid (4-nitro-phenyl) ester (2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl) ester

HRID 55562

반응식

HRID 55562 반응식
[O:1]=[C:2]1[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:5]2[CH:13]=[C:14]([O:17][C:18](=[O:22])[C:19](Cl)=[O:20])[CH:15]=[CH:16][C:4]=2[O:3]1.[CH:23]1[C:28]([N+:29]([O-:31])=[O:30])=[CH:27][CH:26]=[C:25]([OH:32])[CH:24]=1>C1(C)C=CC=CC=1>[O:1]=[C:2]1[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:5]2[CH:13]=[C:14]([O:17][C:18](=[O:22])[C:19]([O:32][C:25]3[CH:24]=[CH:23][C:28]([N+:29]([O-:31])=[O:30])=[CH:27][CH:26]=3)=[O:20])[CH:15]=[CH:16][C:4]=2[O:3]1

참가 물질

4

반응물 2

HCID 9804-NitrophenolHCID 53805502Chloro-oxo-acetic acid 2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl ester

생성물 1

HCID 86750781Oxalic acid (4-nitro-phenyl) ester (2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl) ester수율 33%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Reaction of chloro-oxo-acetic acid 2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl ester prepared as Example 11 reacted in toluene at the reflux with p-nitrophenol gave after purification oxalic acid (4-nitro-phenyl) ester (2-oxo-3-phenyl-2,3-dihydro-benzofuran-5-yl) ester (33% yield). Analysis C,63.5; H,3.3; N,3.5; C22H13NO8 requires C,63.0; H,3.1; N,3.3%. Mass Spectrometry shows a molecular ion at 419.

후처리

  1. customgave

출처 및 근거

ORD 기록
ord-4efc249eec60465d8c0a6c8fbc253e0a
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05625080

연결된 노트

불러오는 중…