4-Methoxycyclohexanol (cis,trans) → 4-Methoxycyclohexanone
반응식
[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][CH:6]([OH:9])[CH2:5][CH2:4]1.[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH3:1][O:2][CH:3]1[CH2:8][CH2:7][C:6](=[O:9])[CH2:5][CH2:4]1참가 물질
4
실험 절차
4-Methoxycyclohexanol (2.0 g, 15.0 mmol) was taken up in 150 mL of DCM. Pyridinium chlorochromate (5.0 g, 23.0 mmol) was added. After 60 hours, the mixture was filtered through a plug of Florisil and concentrated under reduced pressure. The residue was taken up in 50 mL of ether and filtered through a plug of silica gel. The solvent was removed under reduced pressure, affording 4-methoxycyclohexanone as a light yellow oil.
후처리
- filtrationthe mixture was filtered through a plug of Florisil
- concentrationconcentrated under reduced pressure
- filtrationfiltered through a plug of silica gel
- customThe solvent was removed under reduced pressure
출처 및 근거
- ORD 기록
- ord-f507dd16125c411db6001cdd6e80706a
- 출처 데이터셋
- uspto-grants-2011_11
- 특허 번호
- US08053438B2
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