돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 556530생성일: 2026년 10월 25일

2-Fluoroaniline → 4-Chloro-6-(2-fluoro-phenylamino)-2-methylsulfanyl-pyrimidine-5-carbaldehyde

https://huagongshe.com/reaction/556530

반응식

참여 물질

역할이름HCID투입량
반응물2-FluoroanilineHCID 9584—
반응물4,6-Dichloro-2-(methylsulfanyl)pyrimidine-5-carbaldehydeHCID 4614004—
생성물4-Chloro-6-(2-fluoro-phenylamino)-2-methylsulfanyl-pyrimidine-5-carbaldehydeHCID 9944073—

반응 단계

Prepared as described above in Example 2 starting from 4,6-dichloro-2-methylsulfanyl-pyrimidine-5-carbaldehyde and 2-fluoroaniline to give the title compound 4-chloro-6-(2-fluoro-phenylamino)-2-methylsulfanyl-pyrimidine-5-carbaldehyde. 1H-NMR: δ 2.53 (s, 3H), 7.15 (m, 3H), 8.25 (m, 1H), 7.44 (m, 1H), 10.31 (s, 1H), 11.35 (br s, 1H). LC MS (m/e)=298 (MH+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08058282B2
출처 데이터셋uspto-grants-2011_11
ORD IDord-10f089b19b9d461eb5e1b395fdd72793
출처 메모uspto-grants-2011_11