2,4-Difluorobenzaldehyde → bis((E)-2,4-Difluorostyrylsulfonyl)methane

HRID 557097노트

반응식

HRID 557097 반응식
[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1[CH:4]=O.C([CH2:14][S:15]([CH2:18][S:19]([CH2:22][C:23](O)=O)(=[O:21])=[O:20])(=[O:17])=[O:16])(O)=O>C(O)(=O)C>[F:1][C:2]1[CH:9]=[C:8]([F:10])[CH:7]=[CH:6][C:3]=1/[CH:4]=[CH:14]/[S:15]([CH2:18][S:19](/[CH:22]=[CH:23]/[C:7]1[CH:6]=[CH:3][C:2]([F:1])=[CH:9][C:8]=1[F:10])(=[O:21])=[O:20])(=[O:17])=[O:16]

참가 물질

4

반응물 2

HCID 737702,4-DifluorobenzaldehydeHCID 2252641Acetic acid, 2,2'-[methylenebis(sulfonyl)]bis-

생성물 1

HCID 11654673bis((E)-2,4-Difluorostyrylsulfonyl)methane수율 75%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A solution of 2,4-difluorobenzaldehyde (2 mmol) and carboxymethane-sulfonylmethanesulfonyl-acetic acid (1 mmol) in acetic acid (10 mL) was subjected to General Procedure 1, to yield the title compound in 75% yield. m.p. 193-195° C.

출처 및 근거

ORD 기록
ord-298e2bf688de494baeb371806b41bf52
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08058313B2

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