참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Propionyl chloride | HCID 62324 | — |
| 반응물 | 2-(Phenylamino)Benzamide | HCID 96455 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 2-Ethyl-1-phenyl-1H-quinazolin-4-one | HCID 66991027 | — |
반응 단계
2.0 g (9.42 mmol) 2-phenylamino-benzamide were dissolved in 30 ml trichloromethane the solution was cooled to 0° C., and 2.61 g (2.44 ml, 28.2 mmol) propionyl chloride was added slowly. The mixture was boiled for 90 minutes and afterwards neutralized with a saturated sodium bicarbonate solution. After evaporation the substance was crystallized from isopropanol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08058431B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_11 |
|---|
| ORD ID | ord-3a03597141834694b183180e548982e9 |
|---|
| 출처 메모 | uspto-grants-2011_11 |
|---|
