2-Methyl-4-oxo-4H-chromene-8-carbaldehyde → HCID 66991397, 화합물

HRID 557418노트

반응식

HRID 557418 반응식
[CH3:1][C:2]1[O:3][C:4]2[C:9]([C:10](=[O:12])[CH:11]=1)=[CH:8][CH:7]=[CH:6][C:5]=2[CH:13]=O.[C:15]([O:21][CH:22]1[CH2:25][CH2:24][CH2:23]1)(=[O:20])[CH2:16][C:17]([CH3:19])=[O:18]>>[CH3:1][C:2]1[O:3][C:4]2[C:9]([C:10](=[O:12])[CH:11]=1)=[CH:8][CH:7]=[CH:6][C:5]=2[CH:13]=[C:16]([C:17](=[O:18])[CH3:19])[C:15]([O:21][CH:22]1[CH2:23][CH2:24][CH2:25]1)=[O:20]

참가 물질

3

반응물 2

HCID 133748832-Methyl-4-oxo-4H-chromene-8-carbaldehydeHCID 20189390Cyclobutyl 3-oxobutanoate

생성물 1

HCID 66991397HCID 66991397, 화합물

실험 절차

The title compound is prepared in analogy to example 25 (stage 25a) starting from 2-methyl-4-oxo-4H-chromene-8-carbaldehyde (2 g, 10.62 mmol) and cyclobutyl acetoacetate (1.66 g, 10.62 mmol). 3.4 g (98% of theory) of the title compound are obtained as an E/Z isomer mixture.

후처리

  1. customThe title compound is prepared in analogy to example 25 (stage 25a)

출처 및 근거

ORD 기록
ord-f922946af9934939ac80684adc7b88d4
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08058447B2

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