2-Chloro-6-methoxyquinoline → HCID 178515743, 화합물

HRID 55783

반응식

HRID 55783 반응식
Cl[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([O:12]C)[CH:8]=2)[N:3]=1.[NH:14]1[C:18]([C:19]2[CH:24]=[CH:23][C:22](B(O)O)=[CH:21][CH:20]=2)=[N:17][N:16]=[N:15]1>>[NH:17]1[C:18]([C:19]2[CH:24]=[CH:23][C:22]([C:2]3[CH:11]=[CH:10][C:9]4[C:4](=[CH:5][CH:6]=[C:7]([OH:12])[CH:8]=4)[N:3]=3)=[CH:21][CH:20]=2)=[N:14][N:15]=[N:16]1

참가 물질

3

반응물 2

HCID 836472-Chloro-6-methoxyquinoline2회HCID 178514828HCID 178514828, 화합물

생성물 1

HCID 178515743HCID 178515743, 화합물

실험 절차

Followed Scheme 2, A conditions: Starting materials: 2-chloro-6-methoxyquinoline (Intermediate 1) and (4-(1H-tetrazol-5-yl)phenyl)boronic acid. 1H NMR (DMSO-d6, 400 MHz): δ 10.15 (s, 1H), 8.45 (d, 2H), 8.31-8.28 (d, 1H), 8.22-8.12 (m, 3H), 7.98-7.95 (d, 1H), 7.39-7.35 (dd, 1H), 7.21 (s, 1H). MS (ESI): m/z 290.08 [M+H]+.

출처 및 근거

ORD 기록
ord-5a015d89cfdc41f8b462660177f883a5
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09433618B2

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