참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-Bromo-2-Chloroethane | HCID 7849 | — |
| 반응물 | (4-Vinylphenyl)acetonitrile | HCID 3944539 | — |
| 촉매 | Benzyl triethylammonium chloride | HCID 66133 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Sodium Hydroxide | HCID 14798 | — |
| 생성물 | 1-(4-Vinylphenyl)cyclopropanecarbonitrile | HCID 66662641 | — |
반응 단계
A mixture of (4-vinylphenyl)acetonitrile (2.1 g, 0.015 mol), 1-bromo-2-chloro-ethane (1.4 mL, 0.016 mol) and benzyltriethylammonium chloride (0.2 g, 0.0008 mol) in aqueous sodium hydroxide solution (20m, 6 mL) was stirred at 70° C. for 1 h. The reaction mixture was cooled, diluted with water and extracted with ethyl ether. The combined ether layers were washed with water and brine, dried and concentrated to afford the product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08058288B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_11 |
|---|
| ORD ID | ord-6f89eb4704a341899b0d4caa84791139 |
|---|
| 출처 메모 | uspto-grants-2011_11 |
|---|
