Hydroxylamine → N-Hydroxy-3-phenylpropanimidamide

HRID 557995

반응식

HRID 557995 반응식
[C:1]1([CH:7]([CH3:10])C#N)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.NO.[OH:13][N:14]=[C:15]([NH2:22])C1C=CC=CC=1>CCO>[OH:13][N:14]=[C:15]([NH2:22])[CH2:10][CH2:7][C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

5

반응물 3

HCID 787HydroxylamineHCID 157612-PhenylpropionitrileHCID 69186N'-Hydroxybenzenecarboximidamide

생성물 1

HCID 53434815N-Hydroxy-3-phenylpropanimidamide수율 70.5%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Phenylpropionitrile (1 g, 7.6 mmol) was reacted with hydroxylamine (50% in water, 0.94 cm3, 15.2 mmol, 2 eq) in EtOH (7.6 cm3) in the same manner as in the preparation of N′-hydroxybenzimidamide (EtOAc used in extraction) to give the product N′-hydroxy-3-phenylpropanimidamide (0.88 g, 70.5%) as a white solid, mp 42-43° C.

출처 및 근거

ORD 기록
ord-5ecad023390f445d950b11c47ee3d58a
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08062429B2

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