Trifluoromethane → [3-(3-Chloro-5-cyano-phenoxy)-4-ethyl-2-fluoro-phenyl]-acetic acid ethyl ester

HRID 558077

반응식

HRID 558077 반응식
[CH:1](F)(F)F.[CH2:5]([O:7][C:8](=[O:28])[CH2:9][C:10]1[CH:15]=[CH:14][C:13]([CH3:16])=[C:12]([O:17][C:18]2[CH:23]=[C:22]([C:24]#[N:25])[CH:21]=[C:20]([Cl:26])[CH:19]=2)[C:11]=1[F:27])[CH3:6].C([Zn]CC)C>>[CH2:5]([O:7][C:8](=[O:28])[CH2:9][C:10]1[CH:15]=[CH:14][C:13]([CH2:16][CH3:1])=[C:12]([O:17][C:18]2[CH:23]=[C:22]([C:24]#[N:25])[CH:21]=[C:20]([Cl:26])[CH:19]=2)[C:11]=1[F:27])[CH3:6]

참가 물질

4

반응물 3

HCID 6373TrifluoromethaneHCID 66999330[3-(3-Chloro-5-cyano-phenoxy)-2-fluoro-4-methyl-phenyl]-acetic acid ethyl esterHCID 178418750HCID 178418750, 화합물

생성물 1

HCID 11545030[3-(3-Chloro-5-cyano-phenoxy)-4-ethyl-2-fluoro-phenyl]-acetic acid ethyl ester

실험 절차

[3-(3-Chloro-5-cyano-phenoxy)-4-ethyl-2-fluoro-phenyl]-acetic acid ethyl ester (R-32) was prepared from R-23 using the procedure described for R-31 except diethylzinc was used in place of dimethylzinc.

출처 및 근거

ORD 기록
ord-95dca1d90ba64da8b687351cae236ec6
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08063028B2

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