Ammonium Hydroxide → 5-bromo-2-methylbenzenesulfonamide

반응식

[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:12])=[C:6]([S:8](Cl)(=[O:10])=[O:9])[CH:7]=1.[OH-].[NH4+:14]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([CH3:12])=[C:6]([S:8]([NH2:14])(=[O:10])=[O:9])[CH:7]=1

참가 물질

반응물 2

HCID 14923Ammonium Hydroxide

HCID 49621635-Bromo-2-methylbenzene-1-sulfonyl chloride

생성물 1

HCID 24468215-bromo-2-methylbenzenesulfonamide수율 55%

실험 절차

Prepared by general procedure III from 5-Bromo-2-methyl-benzenesulfonyl chloride (1.89 g, 7 mmol) and ammonium hydroxide (20 mL) to give the title compound (0.96 g, 55%) as a white solid. MS (ISN) 248.0 [(M−H)−], 250.0 [(M+2−H)−].

출처 및 근거

ORD 기록: ord-c0470a0ce5964e4cb179cac8b3d39ac8
출처 데이터셋: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08063048B2

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