Morpholine → 4-((3-Bromophenyl)sulphonyl)morpholine

반응식

[Br:1][C:2]1[CH:3]=[C:4]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1.[NH:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1>>[Br:1][C:2]1[CH:3]=[C:4]([S:8]([N:12]2[CH2:17][CH2:16][O:15][CH2:14][CH2:13]2)(=[O:10])=[O:9])[CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 8083Morpholine

HCID 17943m-Bromobenzenesulphonyl chloride

생성물 1

HCID 36960024-((3-Bromophenyl)sulphonyl)morpholine수율 98%

실험 절차

Prepared by general procedure III from 3-bromobenzenesulfonyl chloride (5.0 g, 20 mmol) and morpholine (1.89 g, 22 mmol) to give the title compound (5.9 g, 98%) as a white solid. MS (ISP) 306.1 [(M+H)+].

출처 및 근거

ORD 기록: ord-76574043b4e147229c1fbbe5f9eb76d4
출처 데이터셋: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08063048B2

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