3,6,7-Trimethyloct-6-en-1-yn-3-ol → HCID 117871987, 화합물

HRID 55913노트

반응식

HRID 55913 반응식
[CH3:1][C:2]([OH:12])([CH2:5][CH2:6][C:7]([CH3:11])=[C:8]([CH3:10])[CH3:9])[C:3]#[CH:4].[H][H]>[Pd].CC([O-])=O.CC([O-])=O.[Pb+2]>[CH3:1][C:2]([OH:12])([CH2:5][CH2:6][C:7]([CH3:11])=[C:8]([CH3:10])[CH3:9])[CH2:3][CH3:4]

참가 물질

4

반응물 2

HCID 1036603,6,7-Trimethyloct-6-en-1-yn-3-olHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 117871987HCID 117871987, 화합물

시약·촉매·용매 1

HCID 131709914Lindlars catalyst촉매

반응 조건

온도
45 °C

실험 절차

383.0 g of 3,6,7-trimethyl-6-octen-1-in-3-ol and 0.3 g of Lindlar catalyst (5% Pd+3.5% Pb on CaCO3) are put in an autoclave and heated under nitrogen to a temperature of 45° C. Nitrogen is exchanged by hydrogen (H2) and the reaction mixture put at an absolute pressure of 2 bar. After the calculated amount of hydrogen has been consumed the reaction mixture is filtered and distilled (2 mbar, 115° C.) to obtain 3,6,7-trimethyl-6-octen-3-ol (=compound of formula (Ia)).

후처리

  1. customAfter the calculated amount of hydrogen has been consumed the reaction mixture
  2. filtrationis filtered
  3. distillationdistilled (2 mbar, 115° C.)

출처 및 근거

ORD 기록
ord-944957ec93d547bca8026a8cecdec329
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09434676B2

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