Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-((9H-Fluoren-9-ylmethoxy)carbonyl)-S-(triphenylmethyl)-L-cysteine → Fmoc-Cys(Trt)-OMe
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-((9H-Fluoren-9-ylmethoxy)carbonyl)-S-(triphenylmethyl)-L-cysteine | HCID 128239 | — |
| 반응물 | Trimethylsilyldiazomethane | HCID 167693 | — |
| 용매 | Benzene | HCID 241 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | Fmoc-Cys(Trt)-OMe | HCID 59278482 | — |
반응 단계
To a stirred solution of Fmoc-L-Cys(Trt)-OH (2.34 g, 4.00 mmol) in methanol (4.0 mL) and benzene (16 mL) was added TMS-diazomethane (2.40 mL, 4.80 mmol). After 1 hour, the mixture was concentrated in vacuo to afford Fmoc-L-Cys(Trt)-OMe which was used in the next step without purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08063065B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-c83cab7fd06241daad4611fb6fdeb1af |
| 출처 메모 | uspto-grants-2011_11 |