Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Difluoro-5-iodobenzene → C-(3,5-Difluoro-phenyl)-C-(1-pyrrolidin-1-yl-cyclobutyl)-methylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Difluoro-5-iodobenzene | HCID 2778221 | — |
| 반응물 | 1-Pyrrolidin-1-yl-cyclobutanecarbonitrile | HCID 43802773 | — |
| 생성물 | C-(3,5-Difluoro-phenyl)-C-(1-pyrrolidin-1-yl-cyclobutyl)-methylamine | HCID 59197902 | — |
반응 단계
The title compound, yellow oil, MS: m/e=267.2 [(M+H)+], was prepared in accordance with the general method of intermediate K from 1-pyrrolidin-1-yl-cyclobutanecarbonitrile (intermediate F) and 3,5-difluoro-iodobenzene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08063098B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-886f9cc5150e40308d57fac948aac89b |
| 출처 메모 | uspto-grants-2011_11 |