N-[2-(3,5-dichloropyridin-2-yl)-2-(2,2,2-trifluoroethoxyimino)ethyl]-2-(trifluoromethyl)benzamide → N-[(2Z)-2-(3,5-dichloro-2-pyridinyl)-2-(2,2,2-trifluoroethoxyimino)ethyl]-2-(trifluoromethyl)benzamide

HRID 56021노트

반응식

HRID 56021 반응식
[Cl:1][C:2]1[C:3]([C:9](=[N:24][O:25][CH2:26][C:27]([F:30])([F:29])[F:28])[CH2:10][NH:11][C:12](=[O:23])[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:19]([F:22])([F:21])[F:20])=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1>C(#N)C>[Cl:1][C:2]1[C:3](/[C:9](=[N:24]\[O:25][CH2:26][C:27]([F:30])([F:28])[F:29])/[CH2:10][NH:11][C:12](=[O:23])[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[C:19]([F:22])([F:21])[F:20])=[N:4][CH:5]=[C:6]([Cl:8])[CH:7]=1

참가 물질

3

반응물 1

HCID 118071540N-[2-(3,5-dichloropyridin-2-yl)-2-(2,2,2-trifluoroethoxyimino)ethyl]-2-(trifluoromethyl)benzamide

생성물 1

HCID 91933929N-[(2Z)-2-(3,5-dichloro-2-pyridinyl)-2-(2,2,2-trifluoroethoxyimino)ethyl]-2-(trifluoromethyl)benzamide수율 80.8%

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

2.6 g of N-[2-(3,5-dichloropyridin-2-yl)-2-(2,2,2-trifluoroethoxyimino)ethyl]-2-(trifluoromethyl)benzamide was dissolved in 12.0 ml of acetonitrile, and the solution was irradiated with light for 48 hours in a quartz cell (manufactured by Fine, 4 clear windows for spectroscopy) using a 100 W high-pressure mercury lamp (manufactured by USHIO INC., lamp: UM-102, power supply: UM-103B-B). After completion of the reaction, the solvent was evaporated under reduced pressure, and the resulting residue was washed with 20 ml of hexane to obtain 2.1 g of the desired product as white crystals.

후처리

  1. customAfter completion of the reaction
  2. customthe solvent was evaporated under reduced pressure
  3. washthe resulting residue was washed with 20 ml of hexane

출처 및 근거

ORD 기록
ord-7ecb6e4c776c484781cb65ae8e1b25dd
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09434684B2

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