HCID 59197938, 화합물 → C-[1-(2-Oxa-6-aza-spiro[3.3]hept-6-yl)-cyclobutyl]-C-phenyl-methylamine

HRID 560217노트

반응식

HRID 560217 반응식
[CH2:1]1[C:4]2([CH2:7][N:6]([C:8]3([C:12]#[N:13])[CH2:11][CH2:10][CH2:9]3)[CH2:5]2)[CH2:3][O:2]1.[C:14]1([Li])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:1]1[C:4]2([CH2:7][N:6]([C:8]3([CH:12]([NH2:13])[C:14]4[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=4)[CH2:11][CH2:10][CH2:9]3)[CH2:5]2)[CH2:3][O:2]1

참가 물질

3

반응물 2

HCID 59197938HCID 59197938, 화합물HCID 178506676HCID 178506676, 화합물

생성물 1

HCID 59197923C-[1-(2-Oxa-6-aza-spiro[3.3]hept-6-yl)-cyclobutyl]-C-phenyl-methylamine

실험 절차

The title compound, yellow oil, MS: m/e=259.1 [(M+H)+], was prepared in accordance with the general method of intermediate B from 1-(2-oxa-6-aza-spiro[3.3]hept-6-yl)-cyclobutanecarbonitrile (intermediate AF) and phenyllithium.

출처 및 근거

ORD 기록
ord-1232e580635841eda008bd70cf9a0a69
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08063098B2

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