Thioacetamide → 5-(3-Fluoro-4-methyl-phenyl)-2-methyl-thiazole-4-carboxylic Acid Methyl Ester

HRID 560241노트

반응식

HRID 560241 반응식
[CH3:1][O:2][C:3](=[O:16])[C:4](=O)[CH:5](Cl)[C:6]1[CH:11]=[CH:10][C:9]([CH3:12])=[C:8]([F:13])[CH:7]=1.[C:17]([NH2:20])(=[S:19])[CH3:18]>>[CH3:1][O:2][C:3]([C:4]1[N:20]=[C:17]([CH3:18])[S:19][C:5]=1[C:6]1[CH:11]=[CH:10][C:9]([CH3:12])=[C:8]([F:13])[CH:7]=1)=[O:16]

참가 물질

3

반응물 2

HCID 2723949ThioacetamideHCID 648982873-Chloro-3-(3-fluoro-4-methyl-phenyl)-2-oxo-propionic acid methyl ester

생성물 1

HCID 668656705-(3-Fluoro-4-methyl-phenyl)-2-methyl-thiazole-4-carboxylic Acid Methyl Ester

실험 절차

prepared by reaction of 3-chloro-3-(3-fluoro-4-methyl-phenyl)-2-oxo-propionic acid methyl ester with thioacetamide. LC-MS: tR=1.00 min; [M+H]+=266.0.

출처 및 근거

ORD 기록
ord-df956139ba0643a6aade6e904b6613b8
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08063099B2

반응 노트

불러오는 중…