2-Pyrazolylbenzoic acid → 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid[(1s,2s,5r)-3-(2-pyrazol-1-yl-benzoyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amide
반응식
[C@H:1]12[CH2:6][C@H:5]1[CH2:4][NH:3][C@@H:2]2[CH2:7][NH:8][C:9]([C:11]1[N:18]2[C:14]([S:15][CH:16]=[CH:17]2)=[N:13][C:12]=1[CH3:19])=[O:10].[N:20]1([C:25]2[CH:33]=[CH:32][CH:31]=[CH:30][C:26]=2[C:27](O)=[O:28])[CH:24]=[CH:23][CH:22]=[N:21]1>>[N:20]1([C:25]2[CH:33]=[CH:32][CH:31]=[CH:30][C:26]=2[C:27]([N:3]2[CH2:4][C@H:5]3[C@H:1]([CH2:6]3)[C@H:2]2[CH2:7][NH:8][C:9]([C:11]2[N:18]3[C:14]([S:15][CH:16]=[CH:17]3)=[N:13][C:12]=2[CH3:19])=[O:10])=[O:28])[CH:24]=[CH:23][CH:22]=[N:21]1참가 물질
3
반응물 2
생성물 1
실험 절차
prepared by reaction of 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid [(1S,2S,5R)-1-(3-aza-bicyclo[3.1.0]hex-2-yl)methyl]-amide with 2-Pyrazol-1-yl-benzoic acid. LC-MS (basic): tR=1.20 min; [M+H]+=447.1.
출처 및 근거
- ORD 기록
- ord-102ab30bd5db4ba4b76af0f7ce62d0f2