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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 560420생성일: 2026년 10월 26일

3-Methylimidazo[2,1-b]thiazole-2-carboxylic acid → 3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid[(1s,2s,5r)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amide

https://huagongshe.com/reaction/560420

반응식

참여 물질

역할이름HCID투입량
반응물3-Methylimidazo[2,1-b]thiazole-2-carboxylic acidHCID 56965725—
반응물((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanoneHCID 66998654—
생성물3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid[(1s,2s,5r)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-amideHCID 25182533—

반응 단계

prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 3-Methyl-imidazo[2,1-b]thiazole-2-carboxylic acid. LC-MS (basic): tR=0.82 min; [M+H]+=492.3.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08063099B2
출처 데이터셋uspto-grants-2011_11
ORD IDord-ce4470bdefe243388be80ab8e7b77e31
출처 메모uspto-grants-2011_11