Imidazo[2,1-b][1,3]thiazole-6-carboxylic acid → HCID 25181850, 화합물
반응식
[NH2:1][CH2:2][C@H:3]1[N:8]([C:9]([C:11]2[N:12]=[C:13]([CH3:23])[S:14][C:15]=2[C:16]2[CH:17]=[C:18]([CH3:22])[CH:19]=[CH:20][CH:21]=2)=[O:10])[CH2:7][C@H:6]2[C@@H:4]1[CH2:5]2.[S:24]1[CH:28]=[CH:27][N:26]2[CH:29]=[C:30]([C:32](O)=[O:33])[N:31]=[C:25]12>>[CH3:23][C:13]1[S:14][C:15]([C:16]2[CH:17]=[C:18]([CH3:22])[CH:19]=[CH:20][CH:21]=2)=[C:11]([C:9]([N:8]2[CH2:7][C@H:6]3[C@H:4]([CH2:5]3)[C@H:3]2[CH2:2][NH:1][C:32]([C:30]2[N:31]=[C:25]3[N:26]([CH:29]=2)[CH:27]=[CH:28][S:24]3)=[O:33])=[O:10])[N:12]=1참가 물질
3
실험 절차
prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with Imidazo[2,1-b]thiazole-6-carboxylic acid. LC-MS (basic): tR=0.81 min; [M+H]+=478.3.
출처 및 근거
- ORD 기록
- ord-2f4badf525154f47bc49c93cc64bc452
- 출처 데이터셋
- uspto-grants-2011_11