Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Ethyl-3-methyl-1H-pyrazole-5-carboxylic acid → 2-Ethyl-5-methyl-2h-pyrazole-3-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Ethyl-3-methyl-1H-pyrazole-5-carboxylic acid | HCID 2743794 | — |
| 반응물 | ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone | HCID 66998493 | — |
| 생성물 | 2-Ethyl-5-methyl-2h-pyrazole-3-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide | HCID 25182106 | — |
반응 단계
prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone with 2-Ethyl-5-methyl-2H-pyrazole-3-carboxylic acid. LC-MS (basic): tR=0.89 min; [M+H]+=484.3.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08063099B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-03ff6d2a37fd463687d68a11d0ec3745 |
| 출처 메모 | uspto-grants-2011_11 |