Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,2-Dimethylindole-3-carboxylic acid → 1,2-Dimethyl-1h-indole-3-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,2-Dimethylindole-3-carboxylic acid | HCID 2761032 | — |
| 반응물 | ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone | HCID 66998493 | — |
| 생성물 | 1,2-Dimethyl-1h-indole-3-carboxylic acid{(1s,2s,5r)-3-[5-(3-chloro-phenyl)-2-methyl-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide | HCID 25182392 | — |
반응 단계
prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-[5-(3-chloro-phenyl)-2-methyl-thiazol-4-yl]-methanone with 1,2-Dimethyl-1H-indole-3-carboxylic acid. LC-MS (basic): tR=0.93 min; [M+H]+=519.3.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08063099B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-d9437f2920de4f6c98da529618aa2eb3 |
| 출처 메모 | uspto-grants-2011_11 |