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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 560454생성일: 2026년 10월 26일

6-fluoro-4H-1,3-benzodioxine-8-carboxylic acid → 6-Fluoro-4h-benzo[1,3]dioxine-8-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amide

https://huagongshe.com/reaction/560454

반응식

참여 물질

역할이름HCID투입량
반응물6-fluoro-4H-1,3-benzodioxine-8-carboxylic acidHCID 2779901—
반응물[2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanoneHCID 86644211—
생성물6-Fluoro-4h-benzo[1,3]dioxine-8-carboxylic acid{(1s,2s,5r)-3-[2-amino-5-(3-fluoro-phenyl)-thiazole-4-carbonyl]-3-aza-bicyclo[3.1.0]hex-2-ylmethyl}-amideHCID 25182671—

반응 단계

prepared by reaction of [2-Amino-5-(3-fluoro-phenyl)-thiazol-4-yl]-((1S,2S,5R)-2-aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-methanone with 6-Fluoro-4H-benzo[1,3]dioxine-8-carboxylic acid. LC-MS (basic): tR=0.79 min; [M+H]+=513.3.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08063099B2
출처 데이터셋uspto-grants-2011_11
ORD IDord-22bdd5e6d5274bda96b9349ef5936560
출처 메모uspto-grants-2011_11