돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 560510생성일: 2026년 10월 26일

4-Methoxy-3-(trifluoromethyl)benzoic acid → 4-Methoxy-N-[(1S,2S,5R)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-3-trifluoromethyl-benzamide

https://huagongshe.com/reaction/560510

반응식

참여 물질

역할이름HCID투입량
반응물4-Methoxy-3-(trifluoromethyl)benzoic acidHCID 2775295—
반응물((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanoneHCID 66998654—
생성물4-Methoxy-N-[(1S,2S,5R)-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.1.0]hex-2-ylmethyl]-3-trifluoromethyl-benzamideHCID 66998626—

반응 단계

prepared by reaction of ((1S,2S,5R)-2-Aminomethyl-3-aza-bicyclo[3.1.0]hex-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 4-Methoxy-3-trifluoromethyl-benzoic acid. LC-MS (basic): tR=0.96 min; [M+H]+=530.0.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08063099B2
출처 데이터셋uspto-grants-2011_11
ORD IDord-d50217b884ac468d91db249e815fc1d2
출처 메모uspto-grants-2011_11