Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethyl Bromide → 2-(4-Ethoxyphenyl)thiazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethyl Bromide | HCID 6332 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 4-(1,3-Thiazol-2-yl)phenol | HCID 223840 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | 2-(4-Ethoxyphenyl)thiazole | HCID 69160608 | 100% |
반응 단계
To a mixture of 2-(4-hydroxyphenyl)thiazole (21.27 g, 0.12 mol) and K2CO3 (82.93 g, 0.60 mol) in acetone (1000 mL) was added bromoethane (39.24 g, 0.36 mol) with stirring at rt. The reaction mixture was heated at 60° C. for 11 h, then cooled to rt, filtered and concentrated in vacuo to give the title compound as a white solid (24.54 g, 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434695B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-1ffa6d2b914f46358351db5fa944536d |
| 출처 메모 | uspto-grants-2016_09 |