Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromo-4-fluorobenzene → (4-Chloro-2-fluorophenyl)(4-fluorophenyl)methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromo-4-fluorobenzene | HCID 9993 | — |
| 반응물 | alpha-(4-Fluorophenyl)-4-(trifluoromethyl)benzenemethanol | HCID 579773 | — |
| 반응물 | 4-Chloro-2-fluorobenzaldehyde | HCID 2724908 | — |
| 생성물 | (4-Chloro-2-fluorophenyl)(4-fluorophenyl)methanol | HCID 58392437 | — |
반응 단계
The title compound was prepared starting from 4.60 g (26.28 mmol) of 4-bromofluorobenzene and 5.00 g (31.53 mmol) of 4-chloro-2-fluorobenzaldehyde in analogy to the synthesis of the compound from Example 80A. 4.45 g (66% of theory) of the title compound were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08063234B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-4eb600ba820a4f04a7489fc54f54436b |
| 출처 메모 | uspto-grants-2011_11 |