Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Morpholino-5-nitropyridine → 6-(Morpholino)pyridin-3-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Morpholino-5-nitropyridine | HCID 96872 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 6-(Morpholino)pyridin-3-amine | HCID 104059 | 99% |
반응 단계
To a solution of 4-(5-nitropyridin-2-yl)morpholine (3.89 g, 18.60 mmol) in THF (100 mL) was added catalyst Pd/C (0.5 g). The reaction was stirred at rt under H2 overnight, and filtered. The filtrate was concentrated in vacuo to give the title compound as a brown-red solid (3.30 g, 99%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434695B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-5b1937e67df74092b5b2b529a362fe03 |
| 출처 메모 | uspto-grants-2016_09 |