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HCID 58392090, 화합물 → HCID 58392319, 화합물

HRID 561718
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HRID 561718 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([C:17]2[C:25]3[C:20](=[C:21]([CH2:26][S:27][CH3:28])[CH:22]=[CH:23][CH:24]=3)[NH:19][CH:18]=2)([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)[CH3:9])=[CH:4][CH:3]=1.ClC1C=CC(C(C2C=CC(Cl)=CC=2)C2C3C(=C(CS(C)=[O:48])C=CC=3)NC=2)=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:17]2[C:25]3[C:20](=[C:21]([CH2:26][S:27]([CH3:28])=[O:48])[CH:22]=[CH:23][CH:24]=3)[NH:19][CH:18]=2)([C:10]2[CH:11]=[CH:12][C:13]([F:16])=[CH:14][CH:15]=2)[CH3:9])=[CH:6][CH:7]=1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

3

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HCID 58392090HCID 58392090, 화합물HCID 583921253-[Bis(4-chlorophenyl)methyl]-7-[(methylsulfinyl)methyl]-1H-indole

생성물 1

HCID 58392319HCID 58392319, 화합물

실험 절차

The title compound was prepared starting from 300 mg (0.73 mmol) of the compound from Example 289 in analogy to the synthesis of the compound from Example 296. 193 mg (62% of theory) of the target compound were obtained as mixture of diastereomers.

후처리

  1. custom193 mg (62% of theory) of the target compound were obtained as mixture of diastereomers

출처 및 근거

ORD 기록
ord-5292fe9a5b5045cc850e0c6a50e73f1a
출처 데이터셋
uspto-grants-2011_11
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US08063234B2

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