2-Chloronicotinonitrile → 2-Methoxypyridine-3-carbonitrile

HRID 561939

반응식

HRID 561939 반응식
Cl[C:2]1[N:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5].[CH3:10][O:11][Na]>CO>[CH3:10][O:11][C:2]1[N:9]=[CH:8][CH:7]=[CH:6][C:3]=1[C:4]#[N:5]

참가 물질

4

반응물 2

HCID 810792-ChloronicotinonitrileHCID 178418582HCID 178418582, 화합물

생성물 1

HCID 2520992-Methoxypyridine-3-carbonitrile

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

2-Methoxy-nicotinonitrile was prepared according to the literature by reaction of the 2-chloro-nicotinonitrile with MeONa in MeOH according to Dunn, A. D.; Norrie, R.; Heterocycl. Chem.; EN; 24; 1987; 85-89.

출처 및 근거

ORD 기록
ord-82c0823aaeed4fe08e8757f88ab8a5ae
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08063225B2

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