Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Nitrogen → 2-Furanpropanol, tetrahydro-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Nitrogen | HCID 947 | — |
| 반응물 | Borane | HCID 6331 | — |
| 반응물 | 3-(Oxolan-2-yl)propanoic acid | HCID 263161 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Furanpropanol, tetrahydro- | HCID 13020 | — |
반응 단계
To a solution of 3-(tetrahydrofuran-2-yl)propanoic acid (11.5 g, 80.0 mmol) in anhydrous THF (200 mL) was added borane (160 mL, 160 mmol, 1 mol/L in THF) dropwise under N2 and the mixture was stirred at rt overnight. The reaction mixture was quenched with MeOH and concentrated in vacuo to give the title compound, which was used for next step without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434695B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-7a75b33b4b474dd5a6abbe7fc9ad701c |
| 출처 메모 | uspto-grants-2016_09 |