Piperidine → 6-Amino-2-{[(1S)-1-methylbutyl]oxy}-9-[3-(1-piperidinyl)propyl]-7,9-dihydro-8H-purin-8-one
반응식
Cl[CH2:2][CH2:3][CH2:4][N:5]1[C:13]([O:14]C)=[N:12][C:11]2[C:6]1=[N:7][C:8]([O:17][C@@H:18]([CH3:22])[CH2:19][CH2:20][CH3:21])=[N:9][C:10]=2[NH2:16].[NH:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1>>[NH2:16][C:10]1[N:9]=[C:8]([O:17][C@@H:18]([CH3:22])[CH2:19][CH2:20][CH3:21])[N:7]=[C:6]2[C:11]=1[NH:12][C:13](=[O:14])[N:5]2[CH2:4][CH2:3][CH2:2][N:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1참가 물질
3
실험 절차
Prepared similarly to Example 29 from 9-(3-chloropropyl)-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine and piperidine.
출처 및 근거
- ORD 기록
- ord-1d2aecb1be3746678f9ea9024baca4ec
- 출처 데이터셋
- uspto-grants-2011_11
- 특허 번호
- US08067426B2
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