Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3,4-Thiadiazol-2-amine → 3-(1H-indazol-5-yl)-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3,4-Thiadiazol-2-amine | HCID 19909 | — |
| 반응물 | 3-(1H-indazol-5-yl)-2,2-dimethyl-3-phenylpropanoic acid | HCID 59252764 | — |
| 생성물 | 3-(1H-indazol-5-yl)-2,2-dimethyl-3-phenyl-N-(1,3,4-thiadiazol-2-yl)propanamide | HCID 24936730 | — |
반응 단계
The title compound was prepared from 3-(1H-indazol-5-yl)-2,2-dimethyl-3-phenylpropanoic acid (Example 29(d)) (44 mg, 0.15 mmol) and 2-amino-1,3,4-thiadiazole using General Coupling Method A to give 29 mg (51% yield) of Example 30. MS found: (M+H)+=378.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08067447B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-ec9ba265c0d8447a8de3f1035647735b |
| 출처 메모 | uspto-grants-2011_11 |