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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 56350생성일: 2026년 10월 26일

3-tert-butyl-1-methyl-1H-pyrazole-5-carboxylic acid → 2-[4-(5-tert-Butyl-2-methyl-2H-pyrazole-3-carbonyl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-ethanone

https://huagongshe.com/reaction/56350

반응식

참여 물질

역할이름HCID투입량
반응물3-tert-butyl-1-methyl-1H-pyrazole-5-carboxylic acidHCID 720529—
반응물1-(4-Fluorophenyl)-2-(piperazin-1-yl)ethan-1-one dihydrochlorideHCID 42933716—
생성물2-[4-(5-tert-Butyl-2-methyl-2H-pyrazole-3-carbonyl)-piperazin-1-yl]-1-(4-fluoro-phenyl)-ethanoneHCID 2481097691.9%

반응 단계

The title compound was prepared in a similar manner as described in Example 1.2, using 3-tert-butyl-1-methyl-1H-pyrazole-5-carboxylic acid (27.3 mg), and 1-(4-fluorophenyl)-2-(piperazin-1-yl)ethanone dihydrochloride (29.5 mg) as starting materials, to afford the title compound (35.5 mg) as a yellow solid. Exact mass calculated for C21H27FN4O2: 386.2. Found: LCMS m/z=387.5 (M+H+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09434692B2
출처 데이터셋uspto-grants-2016_09
ORD IDord-96434d945b19418f81d8c3ae2719b1d7
출처 메모uspto-grants-2016_09