참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Phosgene | HCID 6371 | — |
| 반응물 | Diisopropylethylamine | HCID 81531 | — |
| 반응물 | N-Ethylbenzylamine | HCID 84352 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Carbamic chloride, N-ethyl-N-(phenylmethyl)- | HCID 10679448 | — |
반응 단계
N-Ethylbenzylamine (0.56 mL, 3.8 mmol) and diisopropylethylamine (1 mL, 5.7 mmol) were combined in CH2Cl2 (12 mL) and cooled to 0° C. Phosgene (20% in toluene; 2.4 mL, 4.6 mmol) was added, and the reaction was stirred overnight at room temperature. The mixture was concentrated, and the residue was dissolved in Et2O and washed twice with H2O. The organic layer was dried, filtered, and concentrated to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08067445B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_11 |
|---|
| ORD ID | ord-2fabad5641c5426cae656d4326331fa4 |
|---|
| 출처 메모 | uspto-grants-2011_11 |
|---|
