5-Bromo-2-iodobenzaldehyde → (4'-Bromo-2'-formyl-6-methoxy-biphenyl-3-yl)-acetic acid ethyl ester

HRID 563755노트

반응식

HRID 563755 반응식
[Br:1][C:2]1[CH:3]=[CH:4][C:5](I)=[C:6]([CH:9]=1)[CH:7]=[O:8].[CH2:11]([O:13][C:14](=[O:33])[CH2:15][C:16]1[CH:21]=[CH:20][C:19]([O:22][CH3:23])=[C:18](B2OC(C)(C)C(C)(C)O2)[CH:17]=1)[CH3:12]>>[CH2:11]([O:13][C:14](=[O:33])[CH2:15][C:16]1[CH:17]=[C:18]([C:5]2[CH:4]=[CH:3][C:2]([Br:1])=[CH:9][C:6]=2[CH:7]=[O:8])[C:19]([O:22][CH3:23])=[CH:20][CH:21]=1)[CH3:12]

참가 물질

3

반응물 2

HCID 219738615-Bromo-2-iodobenzaldehydeHCID 58120060[4-Methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester

생성물 1

HCID 58148806(4'-Bromo-2'-formyl-6-methoxy-biphenyl-3-yl)-acetic acid ethyl ester

실험 절차

Prepared according to the procedure described in Example 1, Step 4, using the following starting materials: 5-bromo-2-iodo-benzaldehyde and [4-methoxy-3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-acetic acid ethyl ester.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-ad1c1b4d455f4f6286bbc9f720748190
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08067445B2

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