Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Bromo-2-fluorobenzaldehyde → (5-Bromo-2-fluorophenyl)methanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Bromo-2-fluorobenzaldehyde | HCID 736327 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | (5-Bromo-2-fluorophenyl)methanol | HCID 2773352 | — |
반응 단계
To a solution of 5-bromo-2-fluorobenzaldehyde (1.3 g, 6.4 mmol) in MeOH (10 mL) was added sodium borohydride (0.29 g, 7.7 mmol), and the reaction was stirred at room temperature for 5 minutes. After aqueous work-up, the residue was purified by silica gel chromatography to give the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08067445B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-e013470df19541eaa101c5ba8cb8d399 |
| 출처 메모 | uspto-grants-2011_11 |